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Distinct Roles of Alpha/Beta Hydrolase Domain Containing Proteins

Anitha Vijayakumar and Ram Rajasekharan

Lipid molecules are not only serve as building blocks of biological membranes but are also progressively documented for their role in various biological processes. Alpha/beta hydrolase domain (ABHD) containing proteins are structurally related with diverse catalytic activities. Members in this family include various enzymes with broad substrate specificities. Proteins from these families are having a conserved ABHD region and lipase and acyltransferase motifs. However, little is known about ABHD proteins in plants. This review discusses about the biological roles and the implications of ABHD domain containing proteins in higher eukaryotes.