Suja Mathan, Vasuki Subramanian and Sajitha Nagamony
The purpose of the present study was to investigate the influence of cultural conditions and environmental parameters affecting the growth and bioactive metabolite production of the seaweed endophytic fungi Aspergillus terreus KC 582297 which exhibits a broad spectrum of in vitro antimicrobial activity against human infecting bacterial pathogens and the high bioactive metabolites production was observed in potato dextrose broth, compared to the other media. Glucose and yeast extract were found to be a best and most suitable carbon and nitrogen sources respectively, for the optimum growth and production of bioactive metabolites. Maximum bioactive metabolite productions occur in pH of 5.5 and temperature at 25°C.
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