Vinay Kumar Mehra, Satish Kumar
Livestock animals are important for agriculture economy and biomedical research. They are sources of mike, meat, egg, leather and other products. The development of genome editing technologies, especially CRISPR-Cas have revolutionized the generation of gene edited farm animals. In this review, we briefly introduce the CRISPR-Cas technology and highlight its application on livestock such as human disease modeling, disease resistant animal, alteration of milk composition, animal welfare and other agricultural and biomedical related traits which enhance the livestock production in order to meet the increasing demand of food worldwide. Besides the several benefits of CRISPR-Cas technology, the risk factors and ethics issues related to this technology should be reconsidered before enter into the CRISPR era.
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