American Journal of Drug Delivery and Therapeutics Offener Zugang

Abstrakt

Comparison of Mouth Opening with Different Non-Surgical Treatment Modalities in Oral Submucous Fibrosis

Karthik PM, Abhijeet Sande, Ashwinirani SR, Ajay Nayak, Renuka Pawar3 and Pankaj Patil

Background: Oral submucous fibrosis (OSMF) is a chronic, complex, irreversible, highly potent pre-cancerous condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the sub mucosal tissues (lamina propria and deeper connective tissues). The condition is linked to oral cancers and is associated with areca nut chewing,the main component of betel quid. Various treatment modalities were compared the efficacy of intraoral administration of vitamin B combined with lycopene with intralesional triamcinolone acetonide combined with hyaluronidase and oral vitamin B complex with lycopene. Objectives: To compare and evaluate the easy, safe and non invasive procedure for treatment of oral submucous fibrosis. Material and Methods: Total of 30 patients with clinically diagnosed OSMF patients. Each group consisted of ten patients with an age ranging from 30 -75years. A thorough case history along with a detailed clinical examination was performed for all individuals. The inter-incisal mouth opening was recorded at initial visit. Each group of patients received different modalities of theraphy for three weeks and mouth opening was measured after three weeks.modalities that were to be compared. Group A Patients were advised use mixture of Turmeric and Jaggery Application twice a day all over the oral mucosa. Group B patients were advised to use Topical Kenacort Application twice a day and Group C patients were advised to do Physiotherapy exercise twice daily.

Results: 30-45 years - It was found that kenacort application suited the best treatment modality for this age group as it showed a very good prognosis in the inter incisal mouth opening. 46-75 years - It was found that jaggery and turmeric application suited the best treatment modality for this age group as it showed a very good prognosis in the inter- incisal mouth opening. Conclusion: In our study group jaggery and turmeric application found to be most easy effective and safe modality of treatment for OSMF patients.