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COVID-19 Presenting Solely as Acute Hemorrhagic Edema of Infancy

Fatima A Dirani, Batoul Kawtharany, Reem Diab, Mostafa Al-Hajj, Rabab El-Hajj

Introduction: The world has been struggling with COVID-19 pandemic for almost 2 years. This health crisis not only affected the medical domain but also has altered the lives of millions of individuals worldwide. The novel coronavirus has been continuously astonishing the scientists with its aggressiveness and multiple presentations. Initially, most patients were expected to present with respiratory symptoms, but the COVID-19 virus took all the medical staff beyond expectations and targeted most human body systems and organs. Many articles are continuously reporting the presence of a wide range of clinical manifestations.

Case description: A two month old baby girl, previously healthy, was referred to our pediatric clinic for an erythematous rash that appeared on her trunk and extremities. This was accompanied with edema of her extremities and a high grade fever that preceded the appearance of the rash by two days. Workup showed a positive COVID-19 infection which was considered the underlying cause after exclusion of any other possible disorder. The rash resolved spontaneously with the end of COVID-19 infection.

Discussion: Although respiratory and gastroenteric symptoms are the most widely known presentations of COVID-19 infection, day after day new manifestations are being documented worldwide. These includes dermatologic signs that are usually self-limited and disappear by the end or soon after the end of the infection.

Conclusion: More studies must be conducted on the SRAS-CoV-2 virus to better understand the reason behind the different manifestations in different individuals. The only solution for this virus so far appears to be vaccination that will distribute immunity throughout the society and eliminate the virus spreading.